Article
Analysis of single nucleotide polymorphisms of CRYGA and CRYGB genes in control population of western Indian origin.
Indian journal of ophthalmology - 1 Jan 2000
Kapur Suman, Mehra Shipra, Gajjar Devarshi, Vasavada Abhay, Kapoor Manav, Sharad Shashwat, Alapure Bhagwat, Rajkumar S
Abstract excerpt
AIM: Polymorphisms in gamma-crystallins ( CRYG ) can serve as markers for lens differentiation and eye disorders leading to cataract. Several investigators have reported the presence of sequence variations within crystallin genes, with or without apparent effects on the function of the proteins both in mice and humans. Delineation of these polymorphic sites may explain the differences observed in the...
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