Article
The associations between three genome-wide risk variants for serum C-peptide of T1D and autoantibody-positive T1D risk, and clinical characteristics in Chinese population.
Journal of human genetics - 1 Mar 2020
Feng Yingjie, Zhang Yuyue, Chen Yang, Chen Shu, Shen Min, Fu Qi, He Yunqiang, Liu Yuwei, Hsu Hsiang-Ting, Xu Xinyu, Chen Heng, Yang Tao, Xu Kuanfeng
Abstract excerpt
AIMS: Recent meta-genome-wide association studies identified several genetic variants associated with beta-cell function in type 1 diabetes (T1D). The aim of this study was to investigate the associations between these variants and T1D risk, C-peptide levels, islet-specific autoantibodies, and lipid levels in Chinese Han population. METHODS: A total of 1005 unrelated autoantibody-positive T1D cases and 1417...
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