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Article

The neuropeptide genes TAC1, TAC3, TAC4, VIP and PACAP(ADCYAP1), and susceptibility to multiple sclerosis.

Journal of neuroimmunology - 1 Feb 2007

Cunningham Stephen, O'Doherty Catherine, Patterson Chris, McDonnell Gavin, Hawkins Stanley, Marrosu Marria G, Vandenbroeck Koen

Abstract excerpt

The related immunomodulatory neuropeptides vasoactive intestinal peptide (VIP) and pituitary adenylyl cyclase activating peptide (PACAP; gene symbol ADCYAP1) have recently been proposed as novel therapeutics for the treatment of multiple sclerosis (MS). These neuropeptides, as well as those belonging to the tachykinin family exert pleiotropic effects, many of which are of relevance to central nervous system...

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Source

Identifiers

PMID: 17175032
DOI: 10.1016/j.jneuroim.2006.11.002

Genes

TAC1
ADCYAP1
VIP
TAC3
TAC4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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