Article
Novel dimeric Nur77 signaling mechanism in endocrine and lymphoid cells.
Molecular and cellular biology - 1 Oct 1997
Philips A, Lesage S, Gingras R, Maira M H, Gauthier Y, Hugo P, Drouin J
Abstract excerpt
Within the nuclear receptor family, Nur77 (also known as NGFI-B) distinguishes itself by its ability to bind a target sequence (the NBRE) as a monomer and by its role in T-cell receptor (TCR)-induced apoptosis in T cells. We now report on a novel mechanism of Nur77 action that is mediated by homo...
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