Article
CD3Z genetic polymorphism in immune response to hepatitis B vaccination in two independent Chinese populations.
PloS one - 1 Jan 2012
Pan Li-Ping, Zhang Wei, Zhang Li, Wu Xiao-Pan, Zhu Xi-Lin, Yan Bing-Yu, Li Jing-Yun, Xu Ai-Qiang, Liu Ying, Li Hui
Abstract excerpt
Vaccination against hepatitis B virus is an effective and routine practice that can prevent infection. However, vaccine-induced immunity to hepatitis B varies among individuals. CD4(+) T helper cells, which play an important role in both cellular and humoral immunity, are involved in the immune response elicited by vaccination. Polymorphisms in the genes involved in stimulating the activation and proliferation of...
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