Article
Polymorphisms in IRG1 gene associated with immune responses to hepatitis B vaccination in a Chinese Han population and function to restrain the HBV life cycle.
Journal of medical virology - 1 Jul 2017
Liu Xing, Zhang Li, Wu Xiao-Pan, Zhu Xi-Lin, Pan Li-Ping, Li Tao, Yan Bing-Yu, Xu Ai-Qiang, Li Hui, Liu Ying
Abstract excerpt
Vaccination against the hepatitis B virus (HBV) is extensively used as an effective method to prevent HBV infection. However, nearly 10% of healthy adults fail to produce a protective level of antibodies against the hepatitis B vaccine, and multiple genetic variants are known to affect the immune response to the hepatitis B vaccine. The aim of the present study was to investigate the association between...
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