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Article

Functional significance of the TLR4/11367 polymorphism identified in Chinese Han population.

Shock (Augusta, Ga.) - 1 Aug 2007

Duan Zhao-xia, Zhu Pei-fang, Dong Hong, Gu Wei, Yang Ce, Liu Qing, Wang Zheng-guo, Jiang Jian-xin

Abstract excerpt

Toll-like receptor 4 (TLR4) is the central signaling receptor for lipopolysaccharide (LPS) in mammals. This study was designed to investigate the functional significance of the G11367C polymorphism, which is a novel variant we identified in the 3' untranslated region of TLR4 gene in Chinese Han population. Three hundred seventy healthy volunteers were selected. The TLR4/11367 polymorphism was genotyped using...

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3' Untranslated Regions
China
TLR4 gene
Genetics, Population
Leukocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lipopolysaccharides

Polymorphism, Single Nucleotide

Toll-Like Receptor 4

Source

Identifiers

PMID: 17529905
DOI: 10.1097/SHK.0b013e31803df782

Genes

TLR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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