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Article

Association between polymorphism of the interleukin-13 gene and susceptibility to hepatocellular carcinoma in the Chinese population.

PloS one - 1 Jan 2015

Deng Yan, Xie Ming, Xie Li, Wang Jian, Li Taijie, He Yu, Li Ruolin, Li Shan, Qin Xue

Abstract excerpt

OBJECTIVE: Interleukin-13 (IL-13) is a potent pleiotropic cytokine that is produced by activated CD4 T cells. This study was undertaken to determine the relationship between two IL-13 gene single nucleotide polymorphisms (SNP rs1800925 and SNP rs20541) and the incidence of hepatitis B virus-related (HBV) hepatocellular carcinoma (HCC). METHOD: Three hundred and ninety-eight HBV-positive individuals (192 HCC and...

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Identifiers

PMID: 25658755
DOI: 10.1371/journal.pone.0116682
PMCID: PMC4319784

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Source receipt: pubmed, retrieved 7 Sept 2026.

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