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Article

Transmembrane interactions of HIV-1 Vpu and tetherin.

Current HIV research - 1 Jun 2012

Guo Fei, Liang Chen

Abstract excerpt

Tetherin is a type II membrane protein that bears a N-terminal transmembrane domain, an extracellular coiled-coil structure and a C-terminal GPI anchor. This unique topology allows tetherin to block the release of a wide range of enveloped viruses from the cell surface. In order to overcome this host restriction, viruses have evolved various counter measures. In the case of human immunodeficiency virus type 1...

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Identifiers

PMID: 22524177
DOI: 10.2174/157016212800792450

Genes

GPI

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Transmembrane interactions of HIV-1 Vpu and tetherin.PMID 22524177Read ↗

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