Regulation of upp expression in Escherichia coli by UTP-sensitive selection of transcriptional start sites coupled with UTP-dependent reiterative transcription.

doi:10.1128/jb.179.21.6665-6673.1997

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Article

Regulation of upp expression in Escherichia coli by UTP-sensitive selection of transcriptional start sites coupled with UTP-dependent reiterative transcription.

Journal of bacteriology - 1 Nov 1997

Tu A H, Turnbough C L

Abstract excerpt

Expression of the upp gene of Escherichia coli, which encodes the pyrimidine salvage enzyme uracil phosphoribosyltransferase, is negatively regulated by pyrimidine availability. In this study, we demonstrate that this regulation occurs mainly by UTP-sensitive selection of alternative transcriptio...

Topics

Escherichia coli
Gene Expression Regulation, Bacterial
Models, Genetic
Mutation
Pentosyltransferases
Promoter Regions, Genetic
RNA, Bacterial
RNA, Messenger
Transcription, Genetic
Uridine Triphosphate

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