Article
Identification of a bacterial regulatory system for ribonucleotide reductases by phylogenetic profiling.
Trends in genetics : TIG - 1 Jul 2005
Rodionov Dmitry A, Gelfand Mikhail S
Abstract excerpt
Using comparative genomics approaches, we analyzed the regulation of ribonucleotide reductase genes in bacterial genomes. A highly conserved palindromic signal with consensus acaCwAtATaTwGtg, named NrdR-box, was identified upstream of most operons encoding ribonuleotide reductases from three different classes. By correlating the occurrence of NrdR-boxes with phylogenetic distribution of ortholog families, we...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
