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Article

A meta-analysis of the relationship of the Parkin p.Val380Leu polymorphism to Parkinson's disease.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Apr 2013

Zhang Yi, Wang Zhen-Zhen, Sun Hong-Mei

Abstract excerpt

Parkinson's disease (PD) is one of the most common movement disorders. Parkin p.Val380Leu polymorphism (c.1239G > C) has been investigated as a potential genetic hallmark of PD, but studies examining the association between the polymorphism and PD have reported conflicting results. Therefore, we conducted a meta-analysis to assess the influence of Parkin p.Val380Leu polymorphism on the susceptibility of PD....

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PMID: 23436552
DOI: 10.1002/ajmg.b.32138

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