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Article

Genetic variations and haplotype diversity of the UGT1 gene cluster in the Chinese population.

PloS one - 1 Jan 2012

Yang Jing, Cai Lei, Huang Haiyan, Liu Bingya, Wu Qiang

Abstract excerpt

Vertebrates require tremendous molecular diversity to defend against numerous small hydrophobic chemicals. UDP-glucuronosyltransferases (UGTs) are a large family of detoxification enzymes that glucuronidate xenobiotics and endobiotics, facilitating their excretion from the body. The UGT1 gene cluster contains a tandem array of variable first exons, each preceded by a specific promoter, and a common set of...

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PMID: 22514612
DOI: 10.1371/journal.pone.0033988
PMCID: PMC3325998

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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