Article
SHP-2 regulates growth factor dependent vascular signalling and function.
Mini reviews in medicinal chemistry - 1 Jan 2014
Mannell Hanna, Krotz Florian
Abstract excerpt
Cellular responses to the environment are mediated by intracellular signalling pathways monitoring several essential cellular processes, such as proliferation, migration, differentiation and survival. Cellular dysfunction is caused by dysregulation of intracelleular signalling pathways and may ultimately result in pathophysiological conditions. The non- transmembrane protein tyrosine phosphatase SHP-2 has been...
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