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Article

Immunohistochemical Detection of MYC-driven Diffuse Large B-Cell Lymphomas

12 Apr 2012

Abstract excerpt

Diffuse large B cell lymphoma (DLBCL) is a clinically and genetically heterogeneous disease. A small subset of DLBCLs has translocations involving the MYC locus and an additional group has a molecular signature resembling Burkitt lymphoma (mBL). Presently, identification of such cases by morphology is unreliable and relies on cytogenetic or complex molecular methods such as gene transcriptional profiling. Herein,...

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PMID: 22511926
DOI: 10.1371/journal.pone.0033813

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