Article
Diffuse large B-cell lymphoma with MYC gene rearrangements: Current perspective on treatment of diffuse large B-cell lymphoma with MYC gene rearrangements; case series and review of the literature.
European journal of cancer (Oxford, England : 1990) - 1 Mar 2016
de Jonge A V, Roosma T J A, Houtenbos I, Vasmel W L E, van de Hem K, de Boer J P, van Maanen T, Lindauer-van der Werf G, Beeker A, Timmers G J, Schaar C G, Soesan M, Poddighe P J, de Jong D, Chamuleau M E D
Abstract excerpt
In the past decade, patients with newly diagnosed diffuse large B-cell lymphoma (DLBCL) were treated with R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone) therapy. Standard treatment is now changing as a result of deeper understanding of underlying biologic differences of such lymphomas. One of the most powerful predictors of an adverse outcome on R-CHOP therapy is the presence of a...
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