Article
Molecular heterogeneity in diffuse large B-cell lymphoma and its implications in clinical diagnosis and treatment.
Biochimica et biophysica acta. Reviews on cancer - 1 Apr 2018
Guo Lingchuan, Lin Pei, Xiong Hui, Tu Shichun, Chen Gang
Abstract excerpt
Over half of patients with diffuse large B-cell lymphoma (DLBCL) can be cured by standard R-CHOP treatment (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone). However, the remaining patients are refractory and ultimately succumb to progressive or relapsed disease. During the past decade, there has been significant progress in the understanding of molecular mechanisms in DLBCL, largely owing...
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