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Article

An intramolecular DNA triplex is disrupted by point mutations associated with hereditary persistence of fetal hemoglobin.

The Journal of biological chemistry - 15 Sept 1992

Ulrich M J, Gray W J, Ley T J

Abstract excerpt

Several investigators have suggested that secondary structures in DNA may be involved with physiologic gene regulatory processes in higher organisms. This hypothesis has been difficult to prove, however, since naturally occurring mutations that alter secondary DNA structures have not yet been identified. In this report, we describe a secondary DNA structure upstream from the human gamma-globin genes; this...

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PMID: 1382059

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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An intramolecular DNA triplex is disrupted by point mutations associated with hereditary persistence of fetal hemoglobin.PMID 1382059Read ↗

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