Kinetics and thermodynamics of triple-helix formation: effects of ionic strength and mismatches.

doi:10.1021/bi00153a021

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Article

Kinetics and thermodynamics of triple-helix formation: effects of ionic strength and mismatches.

Biochemistry - 29 Sept 1992

Rougée M, Faucon B, Mergny J L, Barcelo F, Giovannangeli C, Garestier T, Hélène C

Abstract excerpt

Thermodynamic and kinetic parameters for the triplex-forming reactions between a homopurine-homopyrimidine 22-base-pair duplex (sequence of the purine strand: 5'd[AAAGGAGGAGAAGAAGAAAAAA]3') and the four 22-dN third strands (22 dN: 5'd[TTTCCTCCTCTNCTTCTTTTTT]3', where N = A, C, T, or G) were deter...

Topics

Base Composition
Base Sequence
Kinetics
Magnesium Chloride
Mathematics
Molecular Sequence Data
Mutation
Nucleic Acid Conformation
Nucleic Acid Denaturation
Nucleic Acid Renaturation
Oligodeoxyribonucleotides
Osmolar Concentration
Thermodynamics

Source

Open in PubMed

Identifiers

PMID: 1390713
DOI: 10.1021/bi00153a021

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1390713-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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