Article
Association of killer cell immunoglobulin-like receptor and human leukocyte antigen-C genotype with dry eye disease in a Chinese Han population.
Genetic testing and molecular biomarkers - 1 Aug 2012
Ren Guifang, Shao Tiejun, Zhuang Yunlong, Hu Haipeng, Zhang Xiuping, Huang Jing, Liu Yunxia, Liu Derong
Abstract excerpt
Dry eye is one of the most prevalent eye diseases and dry eye disease (DED) is associated with ocular surface inflammation. The interaction between killer cell immunoglobulin-like receptors (KIRs) and human leukocyte antigens (HLAs) regulates the activation of natural killer (NK) cells and certain T cell subsets in response to inflammation. The objective of this study was to explore whether KIR gene and HLA-C...
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