Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of Human Leukocyte Antigen Polymorphisms With Moderate-to-Severe Dry Eye With and Without Sjögren's Syndrome.

Investigative ophthalmology & visual science - 1 Jul 2025

Chen Zhiqing, Jiang Dan, Zheng Qinxiang, Xing Shilai, Li Jinyang, Lin Lei, Ren Li, Xu Hanlu, Yu Xiaoguang, Tong Louis, Chen Wei

Abstract excerpt

Purpose: Sjögren's syndrome dry eye (SSDE) has been described in relation to human leukocyte antigen (HLA) polymorphisms. It is unknown whether non-Sjögren's syndrome dry eye (NSDE) is related to HLA. This study aimed to evaluate the genetic association of HLA polymorphism with dry eye disease (DED). This was a cross-sectional study. Methods: Patients with moderate-to-severe DED with and without Sjögren's...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Alleles

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cross-Sectional Studies

Share to Gene Frequency

Share to HLA Antigens

Share to Polymorphism, Genetic

Share to Severity of Illness Index

Share to Sjogren's Syndrome

Source

Open in PubMed Open full text

Identifiers

PMID: 40693714
DOI: 10.1167/iovs.66.9.57
PMCID: PMC12302039

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of Human Leukocyte Antigen Polymorphisms With Moderate-to-Severe Dry Eye With and Without Sjögren's Syndrome.PMID 40693714Read ↗

Association of killer cell immunoglobulin-like receptor and human leukocyte antigen-C genotype with dry eye disease in a Chinese Han population.Semantic proximity Read ↗

[Sjögren syndrome].Semantic proximity Read ↗

Unraveling the Pathophysiology of Sjogren Syndrome-Associated Dry Eye DiseaseSemantic proximity Read ↗

Associations between HLA molecules and ophthalmologic diseases.Semantic proximity Read ↗

Conjunctival Inflammatory Gene Expression Profiling in Dry Eye Disease: Correlations With HLA-DRA and HLA-DRB1Semantic proximity Read ↗

Beyond dry eye: how co-morbidities influence disease phenotype in dry eye disease.Semantic proximity Read ↗

Genetic variants associated with Sjögren's disease subtypes stratified by clinical feature.Semantic proximity Read ↗

Personalised Dry Eye Treatment: The Use of Genetic Testing to Tailor Treatment Plans to Individual PatientsSemantic proximity Read ↗

The clinical phenotype of isolated ocular or oral dryness in Sjögren's disease.Semantic proximity Read ↗

Human leukocyte antigen system associations in Malassezia-related skin diseases.Semantic proximity Read ↗

Immunogenetics and clinical phenotype of sympathetic ophthalmia in British and Irish patients.Semantic proximity Read ↗

Predicting Risks of Dry Eye Disease Development Using a Genome-Wide Polygenic Risk Score Model.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.