Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Understanding the killer-cell immunoglobulin like receptor polymorphism in retinoblastoma.

Ophthalmic genetics - 1 Feb 2023

Aggarwal Ritu, Sharma Madhulika, Singh Usha, Poulton Kay, Bhatia Tanvi, Mangat Navdeep, Kakkar Nandita, Bansal Deepak

Abstract excerpt

BACKGROUND: The KIR receptors present on the natural killer (NK) cells play a crucial role by exercising cytotoxicity to eliminate tumor cells. Both KIR and class-I HLA molecules exhibit extensive polymorphism. Although RB1 inactivation triggers the initiation of retinoblastoma; however additional immune alterations trigger tumor development. The aim was to explore the KIR/HLA polymorphism and its role in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child
Share to Child, Preschool
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Immunoglobulins

Share to Infant

Share to Receptors, KIR

Share to Retinal Neoplasms

Share to Retinoblastoma

Source

Identifiers

PMID: 36594723
DOI: 10.1080/13816810.2022.2163404

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Understanding the killer-cell immunoglobulin like receptor polymorphism in retinoblastoma.PMID 36594723Read ↗

Killer-cell immunoglobulin-like receptor genes and ligands and their role in hematologic malignancies.Semantic proximity Read ↗

Killer immunoglobulin-like receptor genes in uveitis.Semantic proximity Read ↗

Association of killer cell immunoglobulin-like receptor gene 2DL1 and its HLA-C2 ligand with family history of cancer in oral squamous cell carcinoma.Semantic proximity Read ↗

Structure/function of human killer cell immunoglobulin-like receptors: lessons from polymorphisms, evolution, crystal structures and mutations.Semantic proximity Read ↗

KIR2DS1, 2DS5, 3DS1 and KIR2DL5 are associated with the risk of head and neck squamous cell carcinoma in Iranians.Semantic proximity Read ↗

Exploration of KIR genes and hematological-related diseases in Chinese Han population.Semantic proximity Read ↗

Analysis of Killer Immunoglobulin-Like Receptor Genes in Colorectal Cancer.Semantic proximity Read ↗

Analysis of killer cell immunoglobulin-like receptors (KIRs) and their HLA ligand genes polymorphisms in Iranian patients with systemic sclerosis.Semantic proximity Read ↗

Genetic polymorphism analysis of killer cell immunoglobulin-like receptor genes in the Chinese Uygur population.Semantic proximity Read ↗

Hanging in the balance. KIR and their role in disease.Semantic proximity Read ↗

Killer cell immunoglobulin-like receptor gene polymorphisms in patients with leukemia: possible association with susceptibility to the disease.Semantic proximity Read ↗

Association of killer cell immunoglobulin-like receptor and human leukocyte antigen-C genotype with dry eye disease in a Chinese Han population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.