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Article

Analysis of killer cell immunoglobulin-like receptors (KIRs) and their HLA ligand genes polymorphisms in Iranian patients with systemic sclerosis.

Clinical rheumatology - 1 Apr 2017

Mahmoudi Mahdi, Fallahian Faranak, Sobhani Soheila, Ghoroghi Shima, Jamshidi Ahmadreza, Poursani Shiva, Dolati Masoumeh, Hosseinpour Zahra, Gharibdoost Farhad

Abstract excerpt

Genetic factors have a great role in the pathogenesis of autoimmune diseases by cooperating with environmental stimuli. Killer immunoglobulin-like receptors (KIRs) are cell surface proteins on NK cells whose association with major histocompatibility complex-I regulates their killing function. The aim of this study was to provide information on the possible association between KIR and human leukocyte antigen (HLA)...

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PMID: 28120169
DOI: 10.1007/s10067-016-3526-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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