Article
Does the Interaction of KIR and HLA Affect the Development of Non-Infectious Uveitis?
Current molecular medicine - 1 Jan 2022
Nakamura Jutaro, Takeuchi Masaki, Ota Masao, Mizuki Nobuhisa, Ohno Shigeaki
Abstract excerpt
Immune tolerance is established in the eye to prevent permanent blindness associated with destructive damage to the cornea and retina caused by immune cell infiltration; hence, the immune responses and subsequent inflammations are strongly suppressed. While non-infectious uveitis develops from a disruption of immune tolerance in the eye, its onset is a result of accumulating etiologic factors, including genetic...
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