Article
Estimating the effect of SNP genotype on quantitative traits from pooled DNA samples.
Genetics, selection, evolution : GSE - 17 Apr 2012
Henshall John M, Hawken Rachel J, Dominik Sonja, Barendse William
Abstract excerpt
BACKGROUND: Studies to detect associations between DNA markers and traits of interest in humans and livestock benefit from increasing the number of individuals genotyped. Performing association studies on pooled DNA samples can provide greater power for a given cost. For quantitative traits, the effect of an SNP is measured in the units of the trait and here we propose and demonstrate a method to estimate SNP...
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