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Article

Interactions between BRCA2 and RAD51 for promoting homologous recombination in Leishmania infantum.

Nucleic acids research - 1 Aug 2012

Genois Marie-Michelle, Mukherjee Angana, Ubeda Jean-Michel, Buisson Rémi, Paquet Eric, Roy Gaétan, Plourde Marie, Coulombe Yan, Ouellette Marc, Masson Jean-Yves

Abstract excerpt

In most organisms, the primary function of homologous recombination (HR) is to allow genome protection by the faithful repair of DNA double-strand breaks. The vital step of HR is the search for sequence homology, mediated by the RAD51 recombinase, which is stimulated further by proteins mediators such as the tumor suppressor BRCA2. The biochemical interplay between RAD51 and BRCA2 is unknown in Leishmania or...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22505581
DOI: 10.1093/nar/gks306
PMCID: PMC3413117

Genes

BRCA2
RAD51

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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