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Homologous Recombination in Protozoan Parasites and Recombinase Inhibitors

7 Sept 2017

Abstract excerpt

Homologous recombination (HR) is a DNA double-strand break (DSB) repair pathway that utilizes a homologous template to fully repair the damaged DNA. HR is critical to maintain genome stability and to ensure genetic diversity during meiosis. A specialized class of enzymes known as recombinases facilitate the exchange of genetic information between sister chromatids or homologous chromosomes with the help of...

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PMID: 28936205
DOI: 10.3389/fmicb.2017.01716

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