GENOVA: gene overlap analysis of GWAS results.

Abstract excerpt

In many published genome-wide association studies (GWAS), the top few strongly associated variants are often located in or near known genes. This observation raises the more general hypothesis that variants nominally associated with a phenotype are more likely to overlap genes than those not associated with a phenotype. We developed a simple approach - named GENe OVerlap Analysis (GENOVA) - to formally test this...

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