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Article

TBL1XR1/TP63: a novel recurrent gene fusion in B-cell non-Hodgkin lymphoma

12 Apr 2012

Abstract excerpt

Recently, the landscape of single base mutations in diffuse large B-cell lymphoma (DLBCL) was described. Here we report the discovery of a gene fusion between TBL1XR1 and TP63, the only recurrent somatic novel gene fusion identified in our analysis of transcriptome data from 96 DLBCL cases. Based on this cohort and a further 157 DLBCL cases analyzed by FISH, the incidence in de novo germinal center B cell-like...

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PMID: 22496164
DOI: 10.1182/blood-2012-02-414441

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