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Article

Polymorphism of genes involved in purine metabolism (XDH, AOX1, MOCOS) in kidney transplant recipients receiving azathioprine.

Therapeutic drug monitoring - 1 Jun 2012

Kurzawski Mateusz, Dziewanowski Krzysztof, Safranow Krzysztof, Drozdzik Marek

Abstract excerpt

BACKGROUND: Xanthine dehydrogenase (XDH), aldehyde oxidase1 (AOX1), and molybdenum cofactor sulfurase (MOCOS) are enzymes involved in purine metabolism. The aim of this study was to investigate single nucleotide polymorphisms (SNPs) in XDH, AOX1, and MOCOS genes in relation to clinical parameters and risk of drug side effects in a cohort of kidney transplant recipients treated with azathioprine (AZA) as a part of...

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Source

Identifiers

PMID: 22495427
DOI: 10.1097/FTD.0b013e31824aa681

Genes

MOCOS
AOX1
XDH
TPMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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