Article
AOX1 and XDH Enzymes Genotyping and its Effect on Clinical Response to Azathioprine in Inflammatory Bowel Disease Patients Among Jordanian Population.
Current drug metabolism - 1 Jan 2020
Mahasneh Sereen, Sharab Ahmad, Al Shhab Mohammad, Rashid Mohammad, Zihlif Malek
Abstract excerpt
BACKGROUND AND OBJECTIVES: Inflammatory bowel disease (IBD) is a set of chronic inflammatory gastrointestinal disorders, which include ulcerative colitis (UC) and Crohn's disease (CD) that affects many patients worldwide with a peak incidence in early adult life. The immunosuppressant drug Azathioprine (AZA) represents one of the most useful drugs in the management of IBD. It is metabolized by many enzymes like...
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