Article
ROR2 gene is associated with risk of non-syndromic cleft palate in an Asian population.
Chinese medical journal - 1 Feb 2012
Wang Hong, Hetmanski Jacqueline B, Ruczinski Ingo, Liang Kung Yee, Fallin M Daniele, Redett Richard J, Raymond Gerald V, Chou Yah-Huei Wu, Chen Philip Kuo-Ting, Yeow Vincent, Chong Samuel S, Cheah Felicia Sh, Jabs Ethylin Wang, Scott Alan F, Beaty Terri H
Abstract excerpt
BACKGROUND: The receptor tyrosine kinase-like orphan receptor 2 (ROR2) gene has been recently shown to play important roles in palatal development in animal models and resides in the chromosomal region linked to non syndromic cleft lip with or without cleft palate in humans. The aim of this study was to investigate the possible association between ROR2 gene and non-syndromic oral clefts. METHODS: Here we tested...
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