Article
Susceptibility locus for non-syndromic cleft lip with or without cleft palate on chromosome 10q25 confers risk in Estonian patients.
European journal of oral sciences - 1 Jun 2010
Nikopensius Tiit, Birnbaum Stefanie, Ludwig Kerstin U, Jagomägi Triin, Saag Mare, Herms Stefan, Knapp Michael, Hoffmann Per, Nöthen Markus M, Metspalu Andres, Mangold Elisabeth
Abstract excerpt
Non-syndromic cleft lip with or without cleft palate (NSCL/P) is one of the most common birth defects and has a multifactorial etiology that includes both genetic and environmental factors. Recently, two novel susceptibility loci and three suggestive loci for NSCL/P were identified by a genome-wide association scan (GWAS) in a German population with subsequent independent replication in a mixed European...
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