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Article

Shift work, circadian gene variants and risk of breast cancer.

Cancer epidemiology - 1 Oct 2013

Grundy Anne, Schuetz Johanna M, Lai Agnes S, Janoo-Gilani Rozmin, Leach Stephen, Burstyn Igor, Richardson Harriet, Brooks-Wilson Angela, Spinelli John J, Aronson Kristan J

Abstract excerpt

Circadian (clock) genes have been linked with several functions relevant to cancer, and epidemiologic research has suggested relationships with breast cancer risk for variants in NPAS2, CLOCK, CRY2 and TIMELESS. Increased breast cancer risk has also been observed among shift workers, suggesting potential interactions in relationships of circadian genes with breast cancer. Relationships with breast cancer of 100...

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Source

Identifiers

PMID: 23725643
DOI: 10.1016/j.canep.2013.04.006

Genes

CLOCK
CRY1
CRY2
NPAS2
PER1
TIMELESS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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