Article
Plasma matrix metalloproteinase 9 as an early surrogate biomarker of advanced colorectal neoplasia.
Gastroenterologia y hepatologia - 1 Jan 2000
Gimeno-García Antonio Z, Triñanes Javier, Quintero Enrique, Salido Eduardo, Nicolás-Pérez David, Adrián-de-Ganzo Zaida, Alarcón-Fernández Onofre, Abrante Beatriz, Romero Rafael, Carrillo Marta, Ramos Laura, Alonso Inmaculada, Ortega Juan, Jiménez Alejandro
Abstract excerpt
INTRODUCTION: Matrix metalloproteinases (MMPs) are overexpressed at different stages of colorectal carcinogenesis and could serve as early surrogate biomarkers of colorectal neoplasia. OBJECTIVE: To assess the utility of plasma MMP2 and MMP9 levels in the detection of advanced colorectal neoplasia and their correlation with tissue levels. METHODS: We analysed blood and tissue samples from patients with...
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