Plasma matrix metalloproteinase 9 as an early surrogate biomarker of advanced colorectal neoplasia.

doi:10.1016/j.gastrohep.2015.10.002

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Article

Plasma matrix metalloproteinase 9 as an early surrogate biomarker of advanced colorectal neoplasia.

Gastroenterologia y hepatologia - 1 Jan 2000

Gimeno-García Antonio Z, Triñanes Javier, Quintero Enrique, Salido Eduardo, Nicolás-Pérez David, Adrián-de-Ganzo Zaida, Alarcón-Fernández Onofre, Abrante Beatriz, Romero Rafael, Carrillo Marta, Ramos Laura, Alonso Inmaculada, Ortega Juan, Jiménez Alejandro

Abstract excerpt

INTRODUCTION: Matrix metalloproteinases (MMPs) are overexpressed at different stages of colorectal carcinogenesis and could serve as early surrogate biomarkers of colorectal neoplasia. OBJECTIVE: To assess the utility of plasma MMP2 and MMP9 levels in the detection of advanced colorectal neoplasia and their correlation with tissue levels. METHODS: We analysed blood and tissue samples from patients with...

Topics

Adenocarcinoma
Adenoma
Adenomatous Polyps
Aged
Area Under Curve
Biomarkers, Tumor
Colonoscopy
Colorectal Neoplasms
Disease Progression
Female
Humans
Male
Matrix Metalloproteinase 2

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Matrix Metalloproteinase 9

Middle Aged

Polymorphism, Single Nucleotide

Prospective Studies

ROC Curve

Source

Open in PubMed

Identifiers

PMID: 26601990
DOI: 10.1016/j.gastrohep.2015.10.002

Genes

MMP9
MMP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.