Article
Vasomotor symptom prevalence is associated with polymorphisms in sex steroid-metabolizing enzymes and receptors.
The American journal of medicine - 1 Sept 2006
Crandall Carolyn J, Crawford Sybil L, Gold Ellen B
Abstract excerpt
The relation of single nucleotide polymorphisms (SNPs) of genes involved in estrogen function to vasomotor symptoms (VMS) has been inadequately explored. We evaluated SNPs in sex steroid-metabolizing genes and estrogen receptors (ERs) for their association with VMS (hot flashes, night sweats, and/or cold sweats) reported by women who were premenopausal or in early perimenopause at baseline. The study population...
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