Polymorphisms in the estrogen synthesis and metabolism pathways and symptoms during the menopausal transition: observations from the Seattle Midlife Women's Health Study.

doi:10.1097/01.gme.0000227058.70903.9f

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Article

Polymorphisms in the estrogen synthesis and metabolism pathways and symptoms during the menopausal transition: observations from the Seattle Midlife Women's Health Study.

Menopause (New York, N.Y.) - 1 Jan 2000

Woods Nancy F, Mitchell Ellen Sullivan, Tao Yun, Viernes Hannah-Malia A, Stapleton Patricia L, Farin Federico M

Abstract excerpt

OBJECTIVE: The purpose of this study was to determine whether polymorphisms in the estrogen synthesis and metabolism pathways are associated with women's vasomotor symptom experiences during the menopausal transition. DESIGN: In 2002, a subset of women enrolled in the Seattle Midlife Women's Health Study since 1990 (N = 174) provided a buccal smear for genotyping. Women were recruited by complete ascertainment of...

Topics

Alleles
Aromatase
Aryl Hydrocarbon Hydroxylases
Body Mass Index
Creatinine
Estrogen Receptor alpha
Estrogens
Estrone
Female
Genotype
Hot Flashes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Menopause

Middle Aged

Polymorphism, Genetic

Statistics, Nonparametric

Vasomotor System

Source

Open in PubMed

Identifiers

PMID: 16977255
DOI: 10.1097/01.gme.0000227058.70903.9f

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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