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Article

Characterization of the 10q26-orthologue in rhesus monkeys corroborates a functional connection between ARMS2 and HTRA1.

Experimental eye research - 1 May 2012

Pahl Lisa, Spangenberg Astrid, Schubert Stephanie, Schönmann Uwe, Schmidtke Jörg, Stuhrmann Manfred

Abstract excerpt

Age-related macular degeneration, which is the leading cause of blindness in industrialized countries, is a multifactorial, degenerative disorder of the macula with strong heritability. For age-related macular degeneration in humans, the genes ARMS2 and HTRA1 in the region 10q26 are both promising candidates for being involved in pathogenesis. However, the associated variants are located in a region of strong...

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Source

Identifiers

PMID: 22465519
DOI: 10.1016/j.exer.2012.03.007

Genes

ARMS2
HTRA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Characterization of the 10q26-orthologue in rhesus monkeys corroborates a functional connection between ARMS2 and HTRA1.PMID 22465519Read ↗

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