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Pharmacogenomics of human P450 oxidoreductase

9 May 2014

Abstract excerpt

Cytochrome P450 oxidoreductase (POR) supports reactions of microsomal cytochrome P450 which metabolize drugs and steroid hormones. Mutations in POR cause disorders of sexual development. P450 oxidoreductase deficiency (PORD) was initially identified in patients with Antley-Bixler syndrome (ABS) but now it has been established as a separate disorder of sexual development (DSD). Here we are summarizing the work on...

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PMID: 24847272
DOI: 10.3389/fphar.2014.00103

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