Article
KRAS mutational status of endoscopic biopsies matches resection specimens.
Journal of clinical pathology - 1 Jul 2012
Yang Qing-Hua, Schmidt Jason, Soucy Genvieve, Odze Robert, Dejesa-Jamanila Liza, Arnold Keely, Kuslich Christine, Lash Richard
Abstract excerpt
AIMS: This study was performed to determine systematically whether KRAS mutational analysis in biopsy tissue is a reliable indicator of KRAS status in subsequent corresponding resection specimens. METHODS: 30 colorectal cancer (CRC) patients with biopsy and corresponding subsequent surgical resection specimens were studied. KRAS mutational analysis was performed on each biopsy sample as well as two separate...
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