Article
Serotonin transporter gene polymorphisms: a case-control study.
Brazilian dental journal - 1 Jan 2012
Abdo Evandro Neves, Correia-Silva Jeane de Fátima, Gomes Carolina Cavaliéri, Pordeus Isabela Almeida, Gomez Ricardo Santiago
Abstract excerpt
Considerable evidence indicates that serotonergic mechanisms, particularly the serotonin transporter, are involved in alcoholism and tobacco use and are influenced by polymorphism of the promoter region of 5HTT (5-HTTLPR). As alcohol and tobacco consumption have been implicated in the pathogenesis of oral cancer, the purpose of this study was to investigate 5-HTTLPR polymorphism in patients with oral squamous...
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