Article
Serotonin transporter gene polymorphism (5-HTTLPR) in patients with recurrent aphthous stomatitis.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Sept 2005
Victoria Junia Maria Netto, Correia-Silva Jeane de Fátima, Pimenta Flávio Juliano, Kalapothakis Evanguedes, Gomez Ricardo Santiago
Abstract excerpt
BACKGROUND: Considerable evidence indicates that serotonergic mechanisms, particularly the serotonin transporter (5-HTT) may be involved in psychological alterations. Recent findings have demonstrated that depression and stress are influenced by polymorphism of the promoter region of 5-HTT (5-HTTLPR) and that the short allele (S) is associated with reduced transcriptional efficiency resulting in reduced serotonin...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.