Article
Association between the STin2 VNTR polymorphism and smoking behavior in oral cancer patients and healthy individuals.
Clinical and experimental medicine - 1 Mar 2012
de Lima Kalil William Alves, Guembarovski Roberta Losi, Oda Julie Massayo Maeda, Ramos Gyl, Oliveira Benedito Valdecir, Cavalli Iglenir João, de Souza Fonseca Ribeiro Enilze Maria, Gonçalves Marlene Silva Bardi, Aoki Mateus Nobrega, Nunes Sandra Odebrecht Vargas, Watanabe Maria Angelica Ehara
Abstract excerpt
The serotonergic system may be involved in smoking behavior since the intake of nicotine increases serotonin secretion in the CNS. Moreover, evidence supporting the beneficial effect of selective serotonin reuptake for quitting smoking suggesting that the serotonin transporter (5-HTT) is a plausible target for the understanding and elucidation of smoking behavior. The transcriptional activity of its human gene...
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