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Article

Integrated analysis of gene copy number, copy neutral LOH, and microRNA profiles in adult acute lymphoblastic leukemia.

Cytogenetic and genome research - 1 Jan 2012

Ninomiya S, Tyybäkinoja A, Borze I, Räty R, Saarinen-Pihkala U M, Usvasalo A, Elonen E, Knuutila S

Abstract excerpt

We adopted an integrated analysis of gene copy number alterations (CNAs), copy number neutral loss of heterozygosity (CNN LOH), and microRNA (miRNA) profiling in 21 adult acute lymphoblastic leukemia (ALL) patients. This study revealed the most frequent CNAs to be at chromosomes 9p, 7, and 17 and recurrent CNN LOH at 5p, 9p, and Xq. As for the most differentially expressed miRNAs, they included 8 upregulated and...

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Source

Identifiers

PMID: 22456238
DOI: 10.1159/000337297

Genes

ABL1
BCR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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