Association of Ku70 A-31G polymorphism and risk of renal cell carcinoma in a Chinese population.

doi:10.1089/dna.2011.1540

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Article

Association of Ku70 A-31G polymorphism and risk of renal cell carcinoma in a Chinese population.

DNA and cell biology - 1 Jul 2012

Wang Wei, Gao Yanqin, Yan Fu, Wang Meilin, Hu Feifei, Wang Dingxian, Cao Qiang, Qin Chao, Yin Changjun, Zhang Zhengdong, Pan Xuping

Abstract excerpt

The DNA repair gene Ku70 plays a key role in the DNA double-strand breaks (DSBs) repair system. Defects in DSBs repair capacity can lead to genomic instability. We hypothesized that the Ku70 A-31G polymorphism (rs132770) was associated with the risk of renal cell carcinoma (RCC). In a hospital-based case-control study of 620 RCC patients and 623 cancer-free controls frequency matched by age and sex, we genotyped...

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PMID: 22455395
DOI: 10.1089/dna.2011.1540

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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