Article
hOGG1 Ser326Cys polymorphism and renal cell carcinoma risk in a Chinese population.
DNA and cell biology - 1 May 2011
Zhao Hu, Qin Chao, Yan Fu, Wu Bin, Cao Qiang, Wang Meilin, Zhang Zhengdong, Yin Changjun
Abstract excerpt
Oxidative DNA damage caused by reactive oxygen species plays an important role in cancer development. Human 8-oxoguanine DNA glycosylase (hOGG1) is involved in base excision repair of 8-oxoguanine from damaged DNA. We hypothesized that variants in the hOGG1 gene are associated with risk of renal...
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