Article
Haplotypes of the D-Amino Acid Oxidase Gene Are Significantly Associated with Schizophrenia and Its Neurocognitive Deficits.
PloS one - 1 Jan 2016
Liu Yu-Li, Wang Sheng-Chang, Hwu Hai-Gwo, Fann Cathy Shen-Jang, Yang Ueng-Cheng, Yang Wei-Chih, Hsu Pei-Chun, Chang Chien-Ching, Wen Chun-Chiang, Tsai-Wu Jyy-Jih, Hwang Tzung-Jeng, Hsieh Ming H, Liu Chen-Chung, Chien Yi-Ling, Fang Chiu-Ping, Faraone Stephen V, Tsuang Ming T, Chen Wei J, Liu Chih-Min
Abstract excerpt
D-amino acid oxidase (DAO) has been reported to be associated with schizophrenia. This study aimed to search for genetic variants associated with this gene. The genomic regions of all exons, highly conserved regions of introns, and promoters of this gene were sequenced. Potentially meaningful single-nucleotide polymorphisms (SNPs) obtained from direct sequencing were selected for genotyping in 600 controls and...
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