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Article

Association of MAOA gene functional promoter polymorphism with CSF dopamine turnover and atypical depression.

Pharmacogenetics and genomics - 1 Apr 2009

Aklillu Eleni, Karlsson Sara, Zachrisson Olof O, Ozdemir Vural, Agren Hans

Abstract excerpt

OBJECTIVE: Monoamine oxidase-A (MAO-A) is a key mitochondrial enzyme that metabolizes biogenic amine neurotransmitters such as dopamine and serotonin. Individuals with atypical depression (AD) are particularly responsive to treatment with MAO inhibitors (MAOIs). Biomarker tests are essential for...

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Source

Identifiers

PMID: 19214141
DOI: 10.1097/FPC.0b013e328328d4d3

Genes

MAOA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19214141-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Association of MAOA gene functional promoter polymorphism with CSF dopamine turnover and atypical depression.PMID 19214141Read ↗

A functional polymorphism in the MAOA gene promoter (MAOA-LPR) predicts central dopamine function and body mass index.Semantic proximity Read ↗

D-amino acid oxidase activator gene (DAOA) variation affects cerebrospinal fluid homovanillic acid concentrations in healthy Caucasians.Semantic proximity Read ↗

A functional polymorphism in the promoter region of MAOA gene is associated with daytime sleepiness in healthy subjects.Semantic proximity Read ↗

A promoter polymorphism in the monoamine oxidase A gene and its relationships to monoamine metabolite concentrations in CSF of healthy volunteers.Semantic proximity Read ↗

A promoter polymorphism in the monoamine oxidase A gene is associated with the pineal MAOA activity in Alzheimer's disease patients.Semantic proximity Read ↗

Associations of a regulatory polymorphism of monoamine oxidase-A gene promoter (MAOA-uVNTR) with symptoms of depression and sleep quality.Semantic proximity Read ↗

MAOA Variants and Genetic Susceptibility to Major Psychiatric Disorders.Semantic proximity Read ↗

Relationship of MAO-A promoter (u-VNTR) and COMT (V158M) gene polymorphisms to CSF monoamine metabolites levels in a psychiatric sample of caucasians: A preliminary report.Semantic proximity Read ↗

Polymorphisms in genes implicated in dopamine, serotonin and noradrenalin metabolism suggest association with cerebrospinal fluid monoamine metabolite concentrations in psychosis.Semantic proximity Read ↗

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