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Article

Cerebrospinal fluid monoamine metabolite concentrations as intermediate phenotypes between glutamate-related genes and psychosis.

Psychiatry research - 30 Sept 2015

Andreou Dimitrios, Söderman Erik, Axelsson Tomas, Sedvall Göran C, Terenius Lars, Agartz Ingrid, Jönsson Erik G

Abstract excerpt

Glutamate-related genes have been associated with schizophrenia, but the results have been ambiguous and difficult to replicate. Homovanillic acid (HVA), 5-hydroxyindoleacetic acid (5-HIAA) and 3-methoxy-4-hydroxyphenylglycol (MHPG) are the major degradation products of the monoamines dopamine, serotonin and noradrenaline, respectively, and their concentrations in the cerebrospinal fluid (CSF), mainly HVA, have...

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Source

Identifiers

PMID: 26142836
DOI: 10.1016/j.psychres.2015.06.023

Genes

DAOA
KMO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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