Article
Implication of AMP-activated protein kinase in transient receptor potential vanilloid type 1-mediated activation of endothelial nitric oxide synthase.
Molecular medicine (Cambridge, Mass.) - 1 Jan 2012
Ching Li-Chieh, Chen Chien-Yu, Su Kuo-Hui, Hou Hsin-Han, Shyue Song-Kun, Kou Yu Ru, Lee Tzong-Shyuan
Abstract excerpt
We investigated whether AMP-activated protein kinase (AMPK), a multi-functional regulator of energy homeostasis, is involved in transient receptor potential vanilloid type 1 (TRPV1)-mediated activation of endothelial nitric oxide synthase (eNOS) in endothelial cells (ECs) and mice. In ECs, treatm...
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